各分子生物学、免疫学、肿瘤学、肝病科学专家:
自噬是继凋亡之后,生命科学最热门的研究领域之一,近年来,自噬研究得到了飞速发展。已经有研究表明,细胞自噬与多种疾病和癌症的发生有关,基于自噬研究的抗癌药物研发也是当前的热门。
虽然,目前已经报告了很多因素能诱导细胞发生自噬,如饥饿、生长因子缺乏、微生物感染、细胞器损伤、蛋白质折叠错误或聚集、DNA损伤、放疗、化疗等等,但是这一过程的详细的信号转到通路和网络仍未完全阐明,这么多刺激信号如何传递的、哪些自噬蛋白接受信号、又有哪些自噬蛋白去执行等很多问题都还在等待进一步解答中。为促进自噬领域最新研究成果的传播,推动转化医学的发展,我们举办中国北京第一届自噬与肝病国际会议,将邀请国内外分子生物学、免疫学、肿瘤学、肝病科学等方面的知名专家、教授,针对当前备受关注的研究热点及问题开展研讨,为广大同行搭建一个相互沟通交流的平台。
主办单位: 首都医科大学附属北京佑安医院,北京市肝病研究所(Capital Medical University, YouAnHospital, Beijing Institute of Hepatology)
会议主席 Chairs: 陈德喜 Dexi Chen,殷晓鸣(Xiao-Ming Yin )
November 8 全天注册registration
November 9
8:00-11:30 Morning session (上午会议)
Moderators (主持人):
Dexi Chen(陈德喜), Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院,北京市肝病研究所)
James Ou, University of Southern California, USA
8:00-8:15 Ni Li (李宁)
首都医科大学附属北京佑安医院院长,北京市肝病研究所所长
Opening Remarks
(开幕词)
The Frontier of Autophagy Research-1(自噬研究前沿-1)
8:15-9: 00 John Lemasters
University of South Carolina, USA
Mitophagy: types, initiators and role in mitochondrial quality control
(线粒体自噬: 类型, 启动机制, 及在线粒体质控中的作用)
Theme 1. Role of Autophagy in Hepatic Homeostasis
(主题1.自噬在肝脏稳态平衡中的作用)
9:05-9:50 Dexi Chen (陈德喜)
Capital Medical University, YouAnHospital, Beijing Institute of Hepatology(首都医科大学附属北京佑安医院,北京市肝病研究所)
Autophagy and the liver diseases
(自噬和肝脏疾病)
9:55-10:40 Wen-Xing Ding (丁文兴)
University of Kansas Medical Center, Kansas City, Kansas, USA
TFEB-mediated lysosome biogenesis in acute-on-chronic alcohol-induced liver injury
(酒精性肝炎中TFEB介导的溶酶体生成机制)
10:45-11:30 Wei An (安威)
首都医科大学基础医学院
Mitophagy and liver regeneration
(线粒体自噬与肝再生)
11:30-1:30 Lunch Break
1:30-5:00 Afternoon session (下午会议)
Moderators (主持人):
Xiao-Ming Yin (殷晓鸣), Indiana University School of Medicine
Feng Ren (任锋), Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院,北京市肝病研究所)
The Frontier of Autophagy Research-2(自噬研究前沿-2)
1:30-2:15 Li Yu (俞立)
清华大学生命科学学院
Mechanism of autophagic lysosome reformation
(自噬性溶酶体再生之机理)
Theme 2. Role of Autophagy in Liver Tumorigenesis
(主题2.自噬在肝癌发生中的作用)
2:20-3:05 Masaaki Komatsu
Niigata University, Japan
Autophagy-specific substrates, p62 and NBR1 serve as drive gene products in hepatocellular carcinoma
(自噬特异性底物p62 和NBR1是肝细胞癌的驱动性基因产物)
3:10-3:55 Huiguo Ding (丁慧国)
Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院,北京市肝病研究所)
Hepatic stellar cells affect the autophagy of hepatocellular carcinoma cells by H2S and its molecular mechanism
(肝星状细胞通过H2S影响肝癌细胞自噬的分子机制)
4:00-4:45 James Ou
University of Southern California, USA
Autophagy and Hepatocarcinogenesis
(自噬和肝细胞癌的发生机制)
4:45-5:00 End of day discussion
November 10
8:00-11:30 Morning session (上午会议)
Moderators (主持人):
John Lemasters, University of South Carolina, USA
Huiguo Ding (丁慧国), Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院,北京市肝病研究所)
The Frontier of Autophagy Research-3(自噬研究前沿-3)
8:15-9: 00 Eeva-LissaEskelina
University of Helsinki, Finland
Dissecting phagophore assembly site using 3D electron microscopy
(用3D电子显微镜术分析自噬膜前体形成的位置)
Theme 3. Role of Autophagy in Hepatic Viral Infection
(主题3.自噬在病毒性肝炎中的作用)
9:05-9:50 Zhengdong Zhao (赵振东)
中国医学科学院病原所
HCV and autophagy
(乙肝病毒和自噬)
9:55-10:40 Aleem Siddiqui
University of California at San Diego, USA
Mitochondrial dynamics, mitophagy and innate immunity in viral hepatitis
(病毒性肝炎中线粒体动态,线粒体自噬和天然免疫的关系)
10:45-11:30 Ying Shi (石英)
Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院,北京市肝病研究所)
Apotentialstrategy to inhibit HBV replication through reducing hepatocytic autophagy
乙型肝炎病毒诱导的自噬及一种通过降低肝细胞自噬抑制HBV复制的新策略
11:30-1:30 LunchBreak
1:30-5:00 Afternoon session (下午会议)
Moderators (主持人):
Wen-Xing Ding (丁文兴), University of Kansas Medical Center, Kansas City, Kansas, USA
Ying Shi (石英), Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院,北京市肝病研究所)
The Frontier of Autophagy Research-4(自噬研究前沿-4)
1:30-2:15 Xiao-Ming Yin (殷晓鸣)
Indiana University School of Medicine, USA
The homeostatic role of autophagy in preventing liver injury
(自噬在预防肝损伤中的稳态作用)
Theme 4. Role of Autophagy in Liver Injury
(主题4.自噬在肝脏损伤中的作用)
2:20-3:05 Feng Ren (任锋)
Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院,北京市肝病研究所)
The Critical role of autophagy in the pathogenesis of liver failure and its molecular regulatory mechanisms
(自噬在肝衰竭病理中的关键作用及分子调节机理)
3:10-3:55 Yu Li (李于)
中国科学院营养研究所Finding a target for Berbering in the liver
(寻找小檗碱在肝脏中的靶点)
4:00-4:45 Xiuhui Li (李秀慧)
Capital Medical University, YouAnHostpical, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院,北京市肝病研究所)
Role of autophagy in the prevention and treatment of acute liver injury by Chinese Medicine
(自噬在中医药防治急性肝损伤中的作用)
4:50-5:00 DexiChen(陈德喜)
Capital Medical University, YouAnHostpical, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院,北京市肝病研究所)
Closing Remarks
(闭幕词)
因通知下发数量有限,各单位可以转发。凡参加培训班的同志,请认真填写下面的报名回执表,寄至:北京市100043-60分箱 邮 编:100043
Nov 08
2017
Nov 13
2017
Registration deadline
2017-11-09 China 北京市
北京第一届自噬与肝病国际会议
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